Alcoholic vs non-alcoholic fatty liver in rats: distinct differences in endocytosis and vesicle trafficking despite similar pathology

Alcoholic vs non-alcoholic fatty liver in rats: distinct differences in endocytosis and vesicle trafficking despite similar pathology.

BACKGROUND Non-alcoholic and alcoholic fatty liver disease (NAFLD and AFLD, respectively) are major health problems, as patients with either condition can progress to hepatitis, fibrosis, and cirrhosis. Although histologically similar, key differences likely exist in these two models. For example, altered content of several vesicle trafficking proteins have been identified in AFLD, but their co...

Pathology of non-alcoholic fatty liver disease.

Non-alcoholic fatty liver disease (NAFLD) covers a spectrum of lesions ranging from steatosis (Non-alcoholic Fatty Liver or NAFL) to a complex pattern with hepatocellular injury and inflammation (non-alcoholic steatohepatitis; NASH) in the absence of alcohol intake. However, it is increasingly clear that intermediate patterns may exist. The histopathological evaluation of liver biopsy samples i...

Lifestyle in Non-alcoholic Fatty Liver: A Review

Background: The world is now in the process of passing on health to non-diseases chronic, like non-alcoholic fatty liver (NAFLD) is a major cause of changes in the lifestyle of people. This study aims to evaluate the effects of lifestyle on fatty liver disease (NAFLD). Methods: For this critical review, we identified articles by searching original studies and review articles published in peer ...

Alcoholic Hepatitis, Alcoholic Cirrhosis & Non-Alcoholic Fatty Liver Disease (NAFLD)

[Non-alcoholic fatty liver disease and non-alcoholic steatohepatitis].

Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are the hepatic manifestations of the metabolic syndrome. Since the prevalence of obesity and consequently of the metabolic syndrome is steadily increasing, the different types of NAFLD are nowadays the most common cause of liver injury in North America. The development of NASH and fatty liver cirrhosis occurs af...